Amine was born in Casablanca, Morocco. He migrated to Canada with this family at the age of 4. He received his Medical Degree and a Master’s of Science from the University of Montreal. After medical school, he joined the Cardiac Surgery Residency program at the University of Toronto, where his clinical interest crystallized around congenital heart disease and complex valve surgery. Amine also has a keen interest in the global burden of heart disease in the developing world, and takes part in yearly surgical missions to countries such as Egypt and Ethiopia.
Amine is currently a PhD candidate in Biomedical Engineering in the University of Toronto’s Institute of Biomaterials & Biomedical Engineering. His research focuses on the generation of the cardiac valve lineage from human embryonic stem cells, and on the generation of human pluripotent stem cell-derived left ventricular cardiomyocytes for the treatment of hypoplastic left heart syndrome.
He is an avid traveler and has visited over 30 countries. His extra-curricular interests include scuba diving, history, language learning, martial arts, and board games.
2020 – PSI Foundation Research Trainee Award
2019 – CSCI/CIHR Resident Research Award
2019 – Joseph M. West Family Memorial Fund
2019 – Edward Christie Stevens Fellowships in Medicine
2019 – Edie Steinberg Scholarship Fund
2019 – Dr. Charles Kerr Award
2019 – CIHR Fellowship Award
2019 – Vanier Canadian Graduate Scholarship [declined]
2019 – Thoracic Surgery Foundation (TSF) Resident Research Fellowship Award
2018 – Peter Munk Research Scholarship
2018 – Canadian Society of Cardiac Surgeons Resident Research Award
2017 – Canadian Cardiovascular Society-Bayer Resident Vascular Awards Finalist
2016 – Annual Cardiology Conference Rockies Resident Research Competition Winner
2016 – MACK Foundation Postgraduate Trainee Bursary
2016 – Canadian Cardiovascular Society Trainee Research Award Finalist
2016 – ACC Rockies Resident Research Competition Winner
Full publication list available on PubMed: https://pubmed.ncbi.nlm.nih.gov/?term=mazine+amine+%5Bauthor%5D&sort=date
Mazine A, El-Hamamsy I, Verma S, Peterson MD, Bonow RO, Yacoub MH, David TE, Bhatt DL. Ross Procedure in Adults for Cardiologists and Cardiac Surgeons: JACC State-of-the-Art Review. J Am Coll Cardiol 2018;72:2761-77.
Mazine A, David TE, Rao V, Hickey EJ, Christie S, Manlhiot C, Ouzounian M. Long-Term Outcomes of the Ross Procedure Versus Mechanical Aortic Valve Replacement: Propensity-Matched Cohort Study. Circulation 2016;134:576-85.
Mazine A, Rocha RV, El-Hamamsy I, Ouzounian M, Yanagawa B, Bhatt DL, Verma S, Friedrich JO. Ross Procedure vs Mechanical Aortic Valve Replacement in Adults: A Systematic Review and Meta-analysis. JAMA Cardiol 2018;3:978-87.
Mazine A, Stevens LM, Ghoneim A, Chung J, Ouzounian M, Dagenais F, El-Hamamsy I, Boodhwani M, Bozinovski J, Peterson MD, Chu MWA; Canadian Thoracic Aortic Collaborative Investigators. Developing Skills for Thoracic Aortic Surgery with Hypothermic Circulatory Arrest. J Thorac Cardiovasc Surg 2018;157:1360-8.
Mikryukov AA, Mazine A, Wei B, Yang D, Miao Y, Gu M, Keller GM. BMP10 Signaling Promotes the Development of Endocardial Cells from Human Pluripotent Stem Cell-Derived Cardiovascular Progenitors. Cell Stem Cell 2020. doi: 10.1016/j.stem.2020.10.003. [Online ahead of print]
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